西藏高原地区237例胃癌构成分析

胃癌是我国常见恶性肿瘤,病死率高,以往报道西藏地区为我国胃癌高发区之一[1],近年来此地区胃癌检出患者不断增多,对人民群众的健康造成严重威胁。为进一步了解高原地区胃癌临床特点,现对我院2009年1月至2012年12月住院治疗的237例胃癌患者的临床资料进行回顾性分析,现报告如下。

Clinical features of gastric cancer in Tibet plateau region: an analysis of 237 cases

Objective To investigate clinical features of 237 gastric cancer patients from plateau region in Tibet. Methods Clinical information of 237 patients with gastric cancer admitted to hospitals in the Tibet region was retrospectively analyzed. Clinical features including sex, age, clinical, endoscopic and histopathologic compositions were statistically compared. Results In all patients, the sex ratio of male to female was 3.2:1; 51.5% were aged from 40 to 59 years; 60.8% were peasants or cadres; 68.4% had tumors in gastric antrum; 82.3% had infiltrated type of gastric cancer; 81.0% presented with lowly-differentiated adenocarcinoma; the positive rate of CEA (carcino-embryonic antigen, as a tumor marker) was 30.0%; 95.2% had stages III to IV cancer evaluated based upon TNM criterion (tumor, node, metastasis). Conclusion In the Tibetan plateau, gastric cancer was commonly seen in gastric antrum of middle-aged or senior men. The severity of carcinoma was high. Effective and comprehensive measures should be actively adopted to prevent and treat gastric cancer in the plateau region according to local clinical features.