非酒精性脂肪肝对脉压及代谢综合征指标改变的观察

目的探讨非酒精性脂肪肝对脉压（PP）及代谢综合征（MS）指标改变的情况。方法对167例非酒精性脂肪肝患者（脂肪肝组）的临床改变及实验室检测结果与非脂肪肝对照组进行比较分析。结果脂肪肝组的体质指数（BMI）、PP、平均动脉压（MAP）、腰围（WC）及腰身比值（腰围／身高，WHtR）均显著高于对照组（P〈0．05或〈0．01）；脂肪肝组伴有高血糖、高血压、高血脂及MS的例数与对照组比较差异均有统计学意义（P〈0．01）。结论非酒精性脂肪肝患者多伴有多种代谢指标异常，遏制脂肪肝的形成和发展，应控制相关的危险因素。

Observation on the changes of pulse pressure and metabolic syndrome-related indexes in patients with nonalcoholic fatty liver disease

Objective To discuss the changes of pulse pressure（PP） and metabolic syndrome（ MS）-related indexes in patients with nonalcoholic fatty liver disease. Methods The data of laboratory examination and the clinical changes in 167 cases of nonalcoholic fatty liver disease（fatty liver group） with those of the control group were com- pared. Results The mean arterial pressure （MAP）, the mean body mass index （BMI）, PP, waist circumference （WC） and waist to height ratio （WHtR） were significantly higher iu fatty liver group than those in control group （ P 〈 0. 05 或 〈 0. 01 ） ; while the cases accompanied with hypertension, hyper blood glucose, hyperlipidemia and MS were increased significantly too （ P 〈 0. 01 ）. Conclusion The patients with nonalcoholic fatty liver disease often accompa- ny with metabolic abnormity. Controlling those risk factors and keeping within limits of fatty liver development would be available to prevent organ function damages.