检测B型尿钠肽对慢性心肾综合征患者诊断和治疗的临床意义

目的探讨B型尿钠肽（BNP）检测对慢性心。肾综合征患者诊断和治疗的临床意义。方法对该院以心脏疾病为基础病的慢性心力衰竭患者54例的临床资料进行回顾性分析，并按照患者人院时血肌肝（Ser）是否≥133mmol／L分为单纯慢性心力衰竭组26例和慢性心肾综合征组28例。结果慢性心肾综合征组的BNP的水平（1321．5±93．88）pg／L明显高于单纯慢性心力衰竭组（865．4±120．32）pg／L（P〈0．05）。两组患者的BNP水平均与左室舒张末期内径（LVEDD）呈正相关，与左室射血分数（LVEF）呈负相关（P〈0．05）。结论BNP检测对慢性心肾综合征患者心功能的诊断、病情的判断、指导治疗以及评估预后有重要意义。

Clinic significance of BNP testing in diagnosis and treatment of patients with chronic cardio-renal syndrome

Objective To understand the clinical significance of BNP in patients with chronic cardio-renal syndrome. Methods The clinical data of 54 chronic heart failure patients with heart disease as underlying disease in the 416 Hospital of Nuclear Industry was retrospectively analyzed. Twenty-six hospitalized patients with simple chronic heart failure（ simple heart failure group）, and 28 hospitalized patients with chronic cardio-renal syndrome（ cardio-re- nal syndrome group） were retrospectively analyzed. Results The BNP level of chronic cardio-renal syndrome group was significantly higher than that of simple heart failure group （ 1321.5 ±93.88） vs （865.4 ±120. 32）pg/L, P 〈 0.05 ） ; The BNP levels of two groups were positively related to the LVEDD and negative related to LVEF （ P 〈 0. 05）. Conclusion BNP can be as applied to cardiac function diagnosis, severity evaluation, therapy guide and prognosis evaluation in patients with chronic cardio-renal syndrome.