阿托伐他汀对老年血脂正常冠心病患者治疗疗效及预后影响

目的：分析阿托伐他汀对老年血脂正常冠心病患者治疗疗效及预后影响。方法：选择本院在2005年2月-2012年6月收治的540例老年血脂正常冠心病患者，按人院顺序分为观察组270例和对照组270例，其中对照组采用常规治疗，对照组采用在常规治疗基础上加用阿托伐他汀治疗，然后观察两组患者的疗效及预后。结果：观察组治疗总有效率94．07％明显高于对照组的81．85％，观察组的临床疗效明显优于对照组患者，比较差异有统计学意义（P〈0．05）。观察组6个月内心绞痛发生率6．67％明显低于对照组的19．62％，急性心肌梗死发生率2．59％明显低于对照组的6．30％，严重心律失常发生率1．11％明显低于对照组的7．78％，心源性死亡发生率0．74％明显低于对照组的1．85％，心血管事件总发生率11．11％明显低于对照组的35．56％。由此可得观察组患者的心血管事件发生情况明显低于对照组，比较差异均有统计学意义（P〈0．05）。结论：阿托伐他汀能提高老年血脂正常冠心病患者治疗疗效、改善患者的预后、值得临床推广应用。

The Effect of Atorvastatin on Curative Effect and Prognosis in Elderly Coronary Artery Disease Patients with Normal Lipid

Objective： To analyze the effect of atorvastatin on curative effect and prognosis in elderly coronary artery disease patients with normal lipid.Method： Five hundred and forty elderly coronary artery disease patients with normal blood lipids in our hospital from February 2005 to June 2012 were selected, according to admission order divided into the observation group and the control group, 270 cases in each group, the control group was treated with conventional treatment, the observation group was treated on the basis of conventional treatment combined with atorvastatin therapy, then the curative effect and prognosis of two groups were observed.Result： The total effective rate of observation group was 94.07%, it was significantly higher than the control group （ 81.85% ）, clinical curative effect of the observation group was obviously better than the control group, the difference was statistically significant （ P〈0.05 ） .Angina incidence of the observation group in six months was 6.67%, it was significandy lower than the control group （ 19.62% ）, acute myocardial infarction incidence of the observation group was 2.59%, it was significantly lower than the control group （ 6.30% ）, severe arrhythmia incidence of the observation group was 1.11%, it was significantly lower than the control group （ 7.78% ）, the incidence of cardiac death was 0.74%, it was significantly lower than the control group （ 1.85% ）, The total incidence of cardiovascular events was 11.11%, it was significantly lower than the control group （ 35.56% ） .The cardiovascular events of the observation group was significantly lower than the control group, there were statistically significant differences between the groups （ P〈0.05 ） .Conclusion： The atorvastatin can improve the curative effect and prognosis of the elderly coronary artery disease patients.It is worthy to be popularized.