| 急性冠状动脉综合征中医证候要素分析 |
| |
| 引用本文： | 王承龙,张大武,王培利,史大卓.急性冠状动脉综合征中医证候要素分析[J].中医杂志,2011(19):1654-1657. |
| |
| 作者姓名： | 王承龙 张大武 王培利 史大卓 |
| |
| 作者单位： | 中国中医科学院西苑医院心血管病中心，北京市海淀区西苑操场1号,100091 |
| |
| 基金项目： | 国家自然科学基金资助项目 |
| |
| 摘 要： | 目的探讨急性冠状动脉综合征(ACS)中医证候要素的分布特点。方法收集经冠状动脉造影证实的ACS患者241例,根据其病史、症状、体征和相关实验室检查进行全球急性冠状动脉事件注册(GRACE)危险评分,并进行中医证候要素分类,使用多因子降维法(MDR)模型筛选出影响ACS预后的具有交互作用的中医证候要素,并且经Logistic回归分析验证。结果 241例ACS患者中血瘀证最为常见213例(88.4%),其次是气虚证、阴虚证、痰浊偏寒证、痰浊偏热证、阳虚证、气滞证;经GRACE危险分层,高危患者21例(8.7%),中低危患者220例(91.3%);应用MDR模型和Logistic回归分析得出Logistic回归方程为:logitP=-2.480+1.969(血瘀+痰浊偏寒+阳虚),发生不良预后危险的比数比例为7.167(OR=7.167,95%CI:1.583,32.441)。结论 ACS患者主要证候要素为血瘀和气虚,出现阳虚+血瘀+痰浊偏寒证的ACS患者较不出现的患者6个月内发生全因死亡事件可能性的百分比要高。
|
| 关 键 词： | 急性冠状动脉综合征 证候要素 全球急性冠状动脉事件注册危险评分 多因子降维模型 |
Analysis on the TCM Syndrome Elements of Acute Coronary Syndrome |
| |
| WANG Chenglong,ZHANG Dawu,WANG Peili,SHI Dazhuo.Analysis on the TCM Syndrome Elements of Acute Coronary Syndrome[J].Journal of Traditional Chinese Medicine,2011(19):1654-1657. |
| |
| Authors: | WANG Chenglong ZHANG Dawu WANG Peili SHI Dazhuo |
| |
| Institution: | WANG Chenglong,ZHANG Dawu,WANG Peili,SHI Dazhuo(Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091) |
| |
| Abstract: | Objective To explore the distribution characteristics of TCM syndrome elements of acute coronary syndrome(ACS).Methods We collect 241 ACS cases confirmed by coronary contrast examination.They were scored with the global registry of acute coronary events(GRACE) according to their medical history,symptoms and signs,and the related laboratory tests.After the TCM syndrome elements were classified,those having influence on the prognosis of ACS and interacting on each other were screened out by using multi-factor... |
| |
| Keywords: | acute coronary syndrome TCM syndrome elements global registry of acute coronary events(GRACE) risk scoring multi-factors dimension reduction(MDR) models |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
