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CT导引下~(125)I粒子植入治疗肝脏恶性肿瘤的临床应用
引用本文:段成洲,王功夏,范斌,郝海芳,李铭.CT导引下~(125)I粒子植入治疗肝脏恶性肿瘤的临床应用[J].临床放射学杂志,2010(1).
作者姓名:段成洲  王功夏  范斌  郝海芳  李铭
作者单位:河南省安阳市肿瘤医院影像科;
摘    要:目的探讨125I放射性粒子近距离照射治疗肝脏恶性肿瘤的近期疗效及副反应。资料与方法按照三维治疗计划系统(TPS)的模拟布源,在螺旋CT导引下局部麻醉进行125I植入,术后1、2、6、12个月随访CT,进行疗效评价。结果17例顺利完成植入手术,无一例发生严重并发症。17例21个病灶中,18个病灶布源满意,满意率85.71%(18/21),5例完全缓解;10例12个病灶部分缓解;稳定2例4个病灶。总有效率80.95%(17/21)。随访2~52个月,5例于半年后失访,2例分别于植入术后7、10个月死亡。另10例中,2例刚植入术后2个月,其他生存1年8例,生存2年3例,生存3年1例,1例已超过52个月。结论CT导引下经皮穿刺植入125I放射性粒子,对肝脏恶性肿瘤有较好局部控制率及较高的安全性。

关 键 词:125I粒子  粒子植入  恶性肿瘤  肝细胞  

Clinical Application of ~(125)I Seeds in the Implantation Treatment of Liver Malignant Tumor Under CT Guidance
DUANG Chengzhou,WANG Gongxia,FAN Bin,et al..Clinical Application of ~(125)I Seeds in the Implantation Treatment of Liver Malignant Tumor Under CT Guidance[J].Journal of Clinical Radiology,2010(1).
Authors:DUANG Chengzhou  WANG Gongxia  FAN Bin  
Institution:DUANG Chengzhou,WANG Gongxia,FAN Bin,et al.Department of Imaging,An Yang Tumor Hospital,Anyang 455000,P.R.China
Abstract:Objective To study the short-term efficacy and side effects of brachytherapy with radioactive 125I seeds for the treatment of liver malignant tumor.Materials and Methods Hilar lesions were examined with contrast enhanced CT before implantation,to understand the anatomic relationship between the lesions and main vessels,bile duct.Three-dimensional treatment planning system(TPS) was used to analog the arrangement of the seeds.,125I seeds were implanted into liver under local anesthesia under spiral CT-guidanc...
Keywords:125I seeds Seeds implantation Malignant tumors  liver cell  
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