Effect of BN 52021, a platelet activating factor antagonist, on dithranol-induced inflammation |
| |
| Authors: | L. KEMÉ NY,M. CSATO,P. BRAQUET,A. DOBOZY |
| |
| Affiliation: | Department of Dermatology, Albert Szent-Gy?rgyi Medical University, Szeged, Hungary. |
| |
| Abstract: | The effect of BN 52021, a selective platelet activating factor (PAF) antagonist was studied on dithranol-induced irritant dermatitis. Pretreatment of the skin with 0.45% BN 52021 ointment significantly suppressed the decrease in capillary resistance, rise in skin temperature and increase in skin-fold thickness produced by dithranol. |
| |
| Keywords: | |
|
|
