获得性免疫缺陷综合征（AIDS）合并播散性弓形虫病尸检的病理学研究

报道美国纽约地区９例播散性弓形虫病尸检材料，均有脑部病变，８例累及心脏，４例累及肺脏，尚见胰腺、消化道、甲状腺、淋巴结、泌尿生殖器官等受累。其中弓形虫性脑炎９例，心肌炎４例，肺炎３例，胰腺炎２例。仅脑炎、肺炎产牛症状，经脑ＣＴ扫描、弓形虫抗体测定提示本病，并经涂片、骨髓活检和尸检证实，以查见弓形虫为依据。临床以神经精神症状和肺部感染症状为主。病变分为静止（潜伏）、组织坏死、炎症反应及增生修复四种状态，强调囊型弓形虫形态学识别的诊断意义。

AIDS complicated with disseminated toxoplasmosis:a pathological study of 9 autopy cases

ine autopsy cases of disseminated toxoplasmosis in New York are reported. Brain were involved in 9 cases, heart in 8, lung in 4,and pancreas,GI tract,thyroid,lymph nodes and urogenital organs were al-so involved.There were toxoplasma encephalitis in 9 cases,myocarditis in 4, pneumonia in 3 and pancreatitis in 2.Only toxoplasma encephalitis and pneumonia produced signs and symptoms leading to diagnosis by CT scan of brain,toxoplasina antibody titer and confirmed by smears,bone marrow biopsy and autopsy based on recognition of encysted toxoplasma. The authors classified the lesions as static(la- tent),necrotic, infiltrative and proliferative status,with the emphasis on the diagnostic significance of identification of toxoplasma,especially its encysted form.