Peripheral nonulcerative keratitis as a presenting sign of microscopic polyangiitis. |
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Authors: | J K Darlington M J Mannis W A Segal V Feiz D E Klug |
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Institution: | Department of Ophthalmology, University of California, Davis, California, USA. |
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Abstract: | PURPOSE: To report a 16-year-old woman who had peripheral keratitis as a presenting sign of microscopic polyangiitis (MPA), which rapidly progressed to acute renal failure. METHOD: Case report. RESULTS: The patient's vasculitis was diagnosed by renal biopsy, which was evaluated with histologic, immunofluorescence, and electron microscopy. The diagnosis was confirmed by laboratory study, which showed a positive antimyeloperoxidase antibody. CONCLUSION: MPA may rarely present with ocular findings and should be considered in the differential diagnosis when a patient has peripheral keratitis. |
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