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Peripheral nonulcerative keratitis as a presenting sign of microscopic polyangiitis.
Authors:J K Darlington  M J Mannis  W A Segal  V Feiz  D E Klug
Institution:Department of Ophthalmology, University of California, Davis, California, USA.
Abstract:PURPOSE: To report a 16-year-old woman who had peripheral keratitis as a presenting sign of microscopic polyangiitis (MPA), which rapidly progressed to acute renal failure. METHOD: Case report. RESULTS: The patient's vasculitis was diagnosed by renal biopsy, which was evaluated with histologic, immunofluorescence, and electron microscopy. The diagnosis was confirmed by laboratory study, which showed a positive antimyeloperoxidase antibody. CONCLUSION: MPA may rarely present with ocular findings and should be considered in the differential diagnosis when a patient has peripheral keratitis.
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