| 自然流产病人免疫治疗后外周血T淋巴细胞亚群的变化 |
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| 引用本文： | 张红岩,刘肖曼,赵晶,徐俐,马守中. 自然流产病人免疫治疗后外周血T淋巴细胞亚群的变化[J]. 齐鲁医学杂志, 2003, 18(4): 398-399 |
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| 作者姓名： | 张红岩 刘肖曼 赵晶 徐俐 马守中 |
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| 作者单位： | 青岛市计划生育科研所,山东,青岛,266071 |
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| 摘 要： | ①目的探讨自然流产病人主动免疫治疗后T淋巴细胞亚群的变化.②方法 30例自然流产妇女采用其配偶静脉血中的淋巴细胞进行免疫治疗,采用抗生物素-生物素-碱性磷酸酶标记的免疫染色方法,对30例妇女的外周血淋巴细胞亚群CD抗原进行检测.③结果经免疫治疗后,CD4+/CD8+比值明显升高(t＝2.65,P＜0.05).④结论自然流产病人免疫治疗后外周血淋巴细胞亚群CD4、CD8抗原检测,可以了解细胞免疫功能的变化,预测疗效.
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| 关 键 词： | 自然流产 免疫治疗 外周血 T淋巴细胞亚群 免疫组织化学 |
| 文章编号： | 1008-0341(2003)04-0398-02 |
| 修稿时间： | 2003-01-10 |
THE CHANGES OF T LYMPHOCYTE SUBSETS IN PERIPHERAL BLOOD IN WOMEN WITH RECURRENT SPONTANEOUS ABORTION FOLLOWING IMMUNOTHERAPY |
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| ZHANG Hong-yan,LIU Xiao-man,ZHAO Jing,et al. THE CHANGES OF T LYMPHOCYTE SUBSETS IN PERIPHERAL BLOOD IN WOMEN WITH RECURRENT SPONTANEOUS ABORTION FOLLOWING IMMUNOTHERAPY[J]. Medical Journal of Qilu, 2003, 18(4): 398-399 |
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| Authors: | ZHANG Hong-yan LIU Xiao-man ZHAO Jing et al |
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| Abstract: | Objective To investigate the changes of T lymphocyte subsets after active immunotherapy for recurrent spontaneous abortion(RSA). Methods Thirty RSA women were immunized with lymphocytes taken from the vein of their spouses. T lymphocyte subsets in peripheral blood from 30 RSA were detected by immunohistochemical method. Results The ratio of CD4 +/CD8 + increased significantly after immunization (t=2.65, P<0.05). Conclusion The detection of CD4 and CD8 antigens of T lymphocyte subsets in peripheral blood of women with RSA may comprehend the cellular immune function and predict the therapeutic efficacy. |
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| Keywords: | abortion habitual immunotherapy active T lymphocyte subsets immunohistochemistry |
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