茶多酚对人膀胱癌BIU-87细胞间隙连接蛋白43表达和细胞间隙连接通讯功能的影响(英文) |
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引用本文: | Zhengguo Cao1,Chao Tian1,Maolin Jiang1,Kui Wu2,Xiaojian Zhong1,Jianxin Li1,Yuefu Han1 1 Department of Urology,The Affiliated Yuebei People’s Hospital of Shantou University Medical College,Shaoguang 512026,China 2 Department of Urology,Anhui Provincial Hospital Affiliated to Anhui Medical College,Hefei 230001,China. 茶多酚对人膀胱癌BIU-87细胞间隙连接蛋白43表达和细胞间隙连接通讯功能的影响(英文)[J]. 中德临床肿瘤学杂志, 2011, 0(12) |
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作者姓名: | Zhengguo Cao1 Chao Tian1 Maolin Jiang1 Kui Wu2 Xiaojian Zhong1 Jianxin Li1 Yuefu Han1 1 Department of Urology The Affiliated Yuebei People’s Hospital of Shantou University Medical College Shaoguang 512026 China 2 Department of Urology Anhui Provincial Hospital Affiliated to Anhui Medical College Hefei 230001 China |
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作者单位: | Zhengguo Cao1,Chao Tian1,Maolin Jiang1,Kui Wu2,Xiaojian Zhong1,Jianxin Li1,Yuefu Han1 1 Department of Urology,The Affiliated Yuebei People’s Hospital of Shantou University Medical College,Shaoguang 512026,China 2 Department of Urology,Anhui Provincial Hospital Affiliated to Anhui Medical College,Hefei 230001,China |
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基金项目: | Supported by a grant from the National Natural Sciences Foundation of China(No.30801138) |
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摘 要: |
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关 键 词: | 人膀胱癌 细胞间隙连接通讯功能 茶多酚 间隙连接蛋白 |
Influence of (-)-epigallocatechin-3-gallate on the expression of connexin43 and gap junction intercellular communication of the bladder cancer cell lines BIU-87 in vitro |
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Abstract: | Objective:The aim of our study was to investigate the effects of(-)-epigallocatechin-3-gallate(EGCG,the major phytochemistry component in green tea)on the expression of connexin43(Cx43)gene and detect the intercellular communication of the human bladder cancer cell lines BIU-87,and explore its possible mechanisms of prevention and cure for the bladder tumor.Methods:The methyl thiazolyl tetrazolium and Annexin-V/PI double-labeled flow cytometry methods were used to observe the growth inhibitory rate(IR)and a... |
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Keywords: | (-)-epigallocatechin-3-gallate bladder tumor connexin43 intercellular communication |
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