Gastric metaplasia in duodenal bulb andCampylobacter-like organisms in development of duodenal ulcer |
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| Authors: | Dr. M. Caselli L. Trevisani A. Aleotti M. R. Bovolenta G. Stabellini |
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| Affiliation: | (1) First Division of Medicine, St. Anna Hospital, Ferrara;(2) Center of Electron Microscopy, University of Ferrara, Ferrara, Italy;(3) C.so B. Rossetti, 34, I-44100 Ferrara, Italy |
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| Abstract: | Multiple biopsies were taken from 50 patients with endoscopic appearance of duodenitis in order to study the relationship between gastric metaplasia in duodenum and the presence ofCampylobacter-like organisms (CLOs) and the development of duodenal ulcer disease. Metaplasia was found in at least one biopsy specimen from 46 of the 50 patients; CLOs were seen in 25 of the 50 patients, only in metaplastic areas. In four cases a  transitional epithelium with the presence of cells containing few apical mucoid granules and absorbent-type brush border as well as goblet cells was seen. In two cases, this epithelium was colonized by a small number of CLOs. Gastric heterotopia appears to be a rare condition. |
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| Keywords: | gastric metaplasia Campylobacter-like organisms Campylobacter pylori duodenitis duodenal ulcer |
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