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Role of specific adrenergic and cholinergic receptors of the blood vessel wall in the regulation of blood clotting during stimulation of the vagus nerve
Authors:V. P. Mishchenko
Abstract:Experiments on dogs showed that if the specific adrenergic receptors of the blood vessel wall (agr- and beta-receptors) were blocked by phentolamine or inderal it still continued to produce tissue blood clotting factors after stimulation of the vagus nerve. No response of this type was observed to stimulation of the nerve after the cholinergic receptors had been blocked by atropine. It is concluded that hyperfibrinolysis and hypercoagulation developing after vagus nerve stimulation are due to excitation of cholinergic structures.Department of Normal Physiology, Chita Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR A. N. Filatov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 78, No. 8, pp. 19–22, August, 1974.
Keywords:adrenergic and cholinergic receptors  vagus nerve  blood clotting
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