Candiduria in intensive care units: association with heavy colonization and candidaemia |
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Authors: | Toya S P Schraufnagel D E Tzelepis G E |
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Affiliation: | University of Athens Medical School and Laiko University Hospital, Athens, Greece. stoya@sbcglobal.net |
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Abstract: | Candiduria is increasingly detected in intensive care unit (ICU) patients and often coexists with candidal colonization at other anatomical sites. Studies involving surgical and medical ICU patients have consistently reported a relationship between candiduria and heavy colonization. This suggests that candiduria could be considered as a marker for heavy colonization. Risk factors that predispose to heavy colonization are generally similar to those predisposing to candidaemia. Candiduria in ICU patients is characterized by a high mortality, largely through a significant relationship with candidaemia, which in some patients may reach 50%. Therapeutic interventions should be strongly considered in the critically ill patient who presents with candiduria and concurrent clinical risk factors predisposing to dissemination. |
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