更昔洛韦治疗尖锐湿疣30例

目的评价更昔洛韦治疗尖锐湿疣的疗效。方法61例尖锐湿疣患者随机分为两组。治疗组30例采用激光祛除疣体后静脉滴注更昔洛韦注射液，0．25g-d^-1qd；对照组30例采用激光祛除疣体后静脉滴注阿昔洛韦注射液，每次0．25g，tid。均连续治疗5d。比较两组实验室检查结果、临床复发率和药物不良反应。结果对照组3个月内复发率为53．33％，治疗组为25．81％，治疗组复发率明显低于对照组（P〈0．05）。两组药物不良反应发生率均较低。结论更昔洛韦治疗尖锐湿疣安全有效，不良反应少。

Ganciclovir in the Treatment of 30 Patients with Condyloma Accuminatum

Objective To assess the therapeutic effectiveness of ganciclovir in the treatment of condyloma accuminatum(CA). Methods Sixty-one patients with CA were randomly divided into 2 groups: the trial group and the control group.Patients of the trial group(n=31,1 case excluded from the group later during the treatment course) and control group(n=30) were given each 0.25 g of ganciclovir and 0.25 g of aciclovir administered by intravenous instillation q.d.for 5 consecutive days,respectively,after the bodies of the warts in all of the patients had been extirpated with laser.The clinical recurrence rates and adverse reactions of the drugs in patients of the 2 groups were compared. Results The recurrence rate of CA within 3 months in patients of the trial group(25.81%) was significantly lower than that in patients of the control group(53.33%)(P<0.05).The incidences of adverse reactions of the drugs in patients of both groups were low. Conclusion Ganciclovir was shown to be safe and effective in the treatment of CA.