Investigating Gata3 as a positional candidate gene for allergic asthma in a murine model |
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Authors: | Li X Wills-Karp M Ewart S |
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Affiliation: | Genetics Graduate Program, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA. |
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Abstract: | Gata3 is a positional candidate gene for allergic asthma. We determined allergen-induced GATA-3 mRNA and protein expression in asthma susceptible and resistant mice and generated Gata3 sequence data. Our data indicate that the Gata3 gene in isolation is not a causative agent of asthma susceptibility in our model. |
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