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Langerhans' cell histiocytosis in an adult patient manifested as recurrent skull lesions and Diabetes Insipidus
Authors:Makras Polyzois  Papadogias Dimitris  Samara Chrysoula  Zetos Athanasios  Kaltsas Gregory  Piaditis George  Chu Antony C
Affiliation:Department of Endocrinology, G. Genimatas General Hospital, Athens Greece.
Abstract:We describe a 57-year old female with the diagnosis of skull and meningeal Langerhans' cell histiocytosis who was treated with the combination of azathioprine and methotrexate. Although the skull lesions improved considerably on this regimen, the patient developed diabetes insipidus while the anterior pituitary function remained intact.
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