| 慢性阻塞性肺疾病患者血清SIL－2R的研究及临床意义 |
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| 引用本文： | 陈绍平,张国元.慢性阻塞性肺疾病患者血清SIL－2R的研究及临床意义[J].华西医学,1996(4). |
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| 作者姓名： | 陈绍平 张国元 |
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| 作者单位： | 川北医学院附属医院 |
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| 摘 要： | 探讨慢性阻塞性肺疾病（ＣＯＰＤ）患者免疫功能的机制。采用双抗体夹心酶联免疫吸附法（ＥＬＩＳＡ）检测２２例ＣＯＰＤ患者及２０例健康对照血清可溶白细胞介素－２受体（ＳＩＬ－２Ｒ）。结果表明：ＣＯＰＤ患者ＳＩＬ－２Ｒ显著高于正常对照，且急性发作期又高于缓解期，差异具显著性（ｐ＜０．００１）；缓解期ＣＯＰＤ患者血清ＳＩＬ－２Ｒ高于健康对照，差异无显著性（０．１＜Ｐ＜０．２）。结果提示：血清ＳＩＬ－２Ｒ增高可能是ＣＯＰＤ患者免疫功能减退与容易发生肺部感染的原因之一。
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| 关 键 词： | 阻塞性肺疾病 受体 白细胞介素－2 |
Clinical Value of Soluble Interleukin-2 Receptor in Patients with Chronic Obstructive Pulmonary Disease |
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| Chen Shaoping, Zhang Guoyuan.Clinical Value of Soluble Interleukin-2 Receptor in Patients with Chronic Obstructive Pulmonary Disease[J].West China Medical Journal,1996(4). |
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| Authors: | Chen Shaoping Zhang Guoyuan |
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| Abstract: | To analyse the mechanism of down-regulation immunity on patients with Chronic obstructive pulmonary disease (COPD). The levels of soluble interleukin-2 receptor (SIL-2R) in 22 patients with COPD and 20 healthy controls were tested by sandwiched ELISA. The levels of SIL-2R were much higher in patients with COPD than those in normal controls respectively (p
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| Keywords: | Pulmonary disease obstructive Receptor interleukin-2 |
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