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枳椇子酒与枳椇子水提取液解酒毒作用比较研究
引用本文:嵇扬,陆红,杨平.枳椇子酒与枳椇子水提取液解酒毒作用比较研究[J].时珍国医国药,2001(6).
作者姓名:嵇扬  陆红  杨平
作者单位:中国人民解放军总后勤部卫生部药品仪器检验所!北京100071(嵇扬),沈阳空军医院!辽宁沈阳110042(陆红),中国人民解放军532医院!安徽黄山245000(杨平)
摘    要:目的 :比较枳子酒与枳子水提取液解酒毒作用。方法 :考察醒酒时间、乙醇浓度、丙二醛含量、谷胱甘肽过氧化物酶活力。结果 :枳子水提取液可明显缩短乙醇诱导的小鼠睡眠时间 ,降低血中乙醇的浓度 ,降低丙二醛含量并能提高谷胱甘肽过氧化物酶活力 ;枳子酒作用不显。结论 :枳子水提取液具解酒毒功效。

关 键 词:枳椇子  酒精中毒  脂质过氧化损伤  小鼠

Comparing Study of Detoxification Effects of Wine and Aqueous Extract of Hovenia dulcis Thunb. on Acute Alcohol Toxicity in mice
JI Yang ,LU Hong ,YANG Ping.Comparing Study of Detoxification Effects of Wine and Aqueous Extract of Hovenia dulcis Thunb. on Acute Alcohol Toxicity in mice[J].Lishizhen Medicine and Materia Medica Research,2001(6).
Authors:JI Yang  LU Hong  YANG Ping
Institution:JI Yang 1,LU Hong 2,YANG Ping 3
Abstract:Objective:To compare the detoxification effects of wine and aqueous extract of Hovenia dulcis Thunb. (HDT) on acute alcohol toxicity in mice.Methods:To investigate sleeping time, alcohol concentration, MDA content and GSH-Px activity.Results:Aqueous extract of HDT can shorten sleeping time induced by alcohol, decrease alcohol concentration, reduce MDA content and increase GSH-Px activity significantly. The wine of HDT can not significantly improve indexes above.Conclusion:The aqueous extract of HDT hsa the effects of relieving alcohol toxicity.
Keywords:Hovenia dulcis Thunb  (HDT)  Alcohol toxicity  Lipoperoxide  Mice
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