| 色氨酸对疟原虫配子体激活因子的影响 |
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| 引用本文： | 王继春,曹雅明,潘琪.色氨酸对疟原虫配子体激活因子的影响[J].中国公共卫生,2003,19(7):794-795. |
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| 作者姓名： | 王继春 曹雅明 潘琪 |
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| 作者单位： | 1. 中国医科大学基础医学院,沈阳,110001
2. 营口市疾病预防控制中心 |
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| 基金项目： | 日美医学合作计划亚洲地区奖励研究事业资助项目( 2 0 0 1) |
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| 摘 要： | 目的 探讨色氨酸代谢产物对斯氏按蚊唾液腺抽提物中疟原虫配子体激活因子的影响。方法 应用柏氏疟原虫体外雄配子体出丝分析方法检测果糖喂饲液中掺入色氨酸后斯氏按蚊唾液腺抽提物疟原虫配子体激活因子的活性变化。结果 斯氏按蚊唾液腺中柏氏疟原虫配子体激活因子与按蚊生长发育程度呈同步变化；喂饲液中掺入色氨酸可增强按蚊唾液腺的出丝诱导活性。结论 喂饲液中掺入色氨酸可提高斯氏按蚊唾液腺中疟原虫配子体激活因子的含量。
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| 关 键 词： | 斯氏按蚊 柏氏疟原虫 唾液腺 色氨酸 配子体激活因子 出丝 |
| 文章编号： | 1001-0580(2003)07-0794-02 |
| 修稿时间： | 2003年5月7日 |
Effect of tryptophan on malaria gametocyte activating factor in salivary glands of anopheles stephensi |
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| WANG Ji chun CAO Ya ming.College of Basic Medical Sciences,China Medical University.Effect of tryptophan on malaria gametocyte activating factor in salivary glands of anopheles stephensi[J].Chinese Journal of Public Health,2003,19(7):794-795. |
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| Authors: | WANG Ji chun CAO Ya mingCollege of Basic Medical Sciences China Medical University |
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| Abstract: | Objective To investigate the effect of tryptophan metabolite in the salivary glands of anopheles stephensi on malaria gametocyte activating factor.Methods The change of activity of malaria gametocyte activating factor in the salivary glands of anopheles stephensi fed on fruoctose supplemented with tryptophan by exflagellation assay of plasmodium berghei in vitro.Results The content of gametocyte activating factor in the salivary gland of anopheles stephensi was related with growth and development of the mosquitoes;exflagellation-inducing activity in the salivary gland was increased by supplementing the diet of mosquito with tryptophan.Conclusion The addition of tryptophan in the diet of mosquito increased the content of malaria gametocyte activating factor in the salivary gland of anopheles stephensi . |
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| Keywords: | anopheles stephensi plasmodium berghei salivary gland tryptophan gametocyte activating factor exflagellation |
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