| 蛋白延长因子eEF1A2在卵巢癌中的作用 |
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| 引用本文： | 曲昌华,李彦红,徐志彦. 蛋白延长因子eEF1A2在卵巢癌中的作用[J]. 中国妇幼健康研究, 2004, 15(6): 398-400 |
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| 作者姓名： | 曲昌华 李彦红 徐志彦 |
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| 作者单位： | 威海市妇女儿童医院,山东,威海,264200;威海市妇女儿童医院,山东,威海,264200;威海市妇女儿童医院,山东,威海,264200 |
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| 摘 要： | 在卵巢癌肿瘤中经常能筛选到20q1213的放大,表明在此区域中至少存在一个重要的原癌基因。其中EEF1A2位于20q13.3,编码蛋白质延长因子eEF1A2。该文主要就EEF1A2是一个重要的卵巢原癌基因及蛋白延长因子网络能激活肿瘤发生并抑制凋亡作一综述。
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| 关 键 词： | 原癌基因 蛋白延长因子 凋亡 |
| 文章编号： | 1008-2514(2004)06-0398-03 |
| 修稿时间： | 2004-04-30 |
A study on protein elongation factor eFFLA2 and its roles in carcinogenesis of ovary |
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| QU Chang hua,LI Yan hong,XU Zhi yan. A study on protein elongation factor eFFLA2 and its roles in carcinogenesis of ovary[J]. Chinese Journal of Maternal and Child Health Research, 2004, 15(6): 398-400 |
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| Authors: | QU Chang hua LI Yan hong XU Zhi yan |
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| Abstract: | That amplication of chromosome 20q12 13 can be screened frequently in ovarian tumors indicates that at least one important oncogene presents in this region. One of the genes is EFFlA2, which is located in 20q13.3 and encodes protein elongation factor eFFlA2. In this review, We summarized current evidences that EFFlA2 is an important ovarian oncogene and that the protein elongation network can activate carcinogenesis and inhibit apoptosis. |
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| Keywords: | oncogene protein elongation factor apoptosis |
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