| 散发性肾透明细胞癌的遗传学研究现状 |
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| 引用本文： | 寿建忠,马建辉. 散发性肾透明细胞癌的遗传学研究现状[J]. 肿瘤研究与临床, 2007, 19(4): 217-220 |
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| 作者姓名： | 寿建忠 马建辉 |
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| 作者单位： | 100021,北京,中国医学科学院中国协和医科大学肿瘤医院泌尿外科 |
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| 摘 要： | 散发性肾透明细胞癌的发生机制十分复杂，不同于遗传性肾癌的单一遗传因素起着决定性作用，但3p缺失、VHL的基因突变等遗传学改变，可能会帮助临床进行肾癌病理亚型的鉴别诊断，基因表达谱中分析的一些标志物可能帮助预测预后
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| 关 键 词： | 肾肿瘤 腺癌 透明细胞 遗传学研究 |
| 收稿时间： | 2007-05-08 |
The current research status of genetics of sporadic clear renal cell carcinoma |
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| SHOU Jian-zhong,MA Jian-hui. The current research status of genetics of sporadic clear renal cell carcinoma[J]. Cancer Research and Clinic, 2007, 19(4): 217-220 |
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| Authors: | SHOU Jian-zhong MA Jian-hui |
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| Abstract: | The mechanism of the development of sporadic renal cell carcinomas is complicated, which is different from that of hereditary renal-cell carcinoma. Genetics abnormality such as loss of 3p, VHLgene mutations may help differentiate pathological subtype of renal cell carcinoma and some gene markers may be useful predictors for prognosis. The current status of genetic study in renal cell carcinomas is reviewed in this article. |
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| Keywords: | Adenocarcinoma clear cell Genetic research |
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