疣状胃炎与胃癌的关系探讨

目的探讨疣状胃炎与胃癌的关系。方法回顾分析778例疣状胃炎病理资料,并与同期862例慢性浅表性胃炎、376例慢性萎缩性胃炎病理资料进行对比。结果疣状胃炎中HP阳性率为82%,显著高于慢性浅表性胃炎（45.1%）和慢性萎缩性胃炎（56.4%）（P〈0.01）。成熟型疣状胃炎肠上皮化生和不典型增生检出率分别为12.7%和14.1%,显著高于慢性浅表性胃炎组（P〈0.01）;与慢性萎缩性胃炎组比较无统计学意义（P〉0.05）。结论成熟型疣状胃炎具有高度癌变的可能,是一种胃癌癌前疾病,应积极治疗和密切随访。

Relationship between varioliform gastritis and gastric cancer

Objective To explore the relationship between varioliform gastritis and precancerous lesion of gastric cancer.Methods The pathological data of varioliform gastritis,chronic superficial gastritis and chronic atrophic gastritis were analyzed retrospectively.Results The positive rate of HP in varioliform gastritis was 82% higher than that in chronic superficial gastritis（45.1%） and chronic atrophic gastritis（56.4%）（P 0.01）.The detection rate of intestinal metaplasia and atypical hyperplasia in mature varioliform gastritis was 12.7% and 14.1% respectively,which were significantly higher than that in chronic superficial gastritis（P 0.01）.There was no difference of the detection rate of intestinal metaplasia and atypical hyperplasia in between varioliform gastritis and chronic atrophic gastritis.Conclusion Mature varioliform gastritis have the potential cancerization,which is precancerous lesion of gastric cancer.