Quantitative magnetic resonance imaging for focal liver lesions: bridging the gap between research and clinical practice |
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| Authors: | Roberto Cannella Riccardo Sartoris Jules Grgory Lorenzo Garzelli Valrie Vilgrain Maxime Ronot Marco Dioguardi Burgio |
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| Institution: | 1. Service de Radiologie, Hôpital Beaujon, APHP.Nord, Clichy, France ; 2. Section of Radiology - BiND, University Hospital “Paolo Giaccone”, Via del Vespro 129, 90127 Palermo, Italy ; 3. Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, 90127 Palermo, Italy ; 4. Université de Paris, Paris, France ; 5. INSERM U1149, CRI, Paris, France |
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| Abstract: | Magnetic resonance imaging (MRI) is highly important for the detection, characterization, and follow-up of focal liver lesions. Several quantitative MRI-based methods have been proposed in addition to qualitative imaging interpretation to improve the diagnostic work-up and prognostics in patients with focal liver lesions. This includes DWI with apparent diffusion coefficient measurements, intravoxel incoherent motion, perfusion imaging, MR elastography, and radiomics. Multiple research studies have reported promising results with quantitative MRI methods in various clinical settings. Nevertheless, applications in everyday clinical practice are limited. This review describes the basic principles of quantitative MRI-based techniques and discusses the main current applications and limitations for the assessment of focal liver lesions. |
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