| 类风湿关节炎患者血脂变化及临床意义 |
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| 引用本文： | 张嵩,刘桂玲,郑岚. 类风湿关节炎患者血脂变化及临床意义[J]. 蚌埠医学院学报, 2011, 36(2): 156-157,160 |
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| 作者姓名： | 张嵩 刘桂玲 郑岚 |
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| 作者单位： | 1. 安徽省蚌埠市第三人民医院血液风湿科, 233000;2. 安徽省蚌埠市第三人民医院检验科, 233000 |
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| 摘 要： | 目的:观察活动期类风湿关节炎(RA)患者血脂的变化及临床意义。方法:选择RA患者56例,其中活动期30例,非活动期26例,另选30例健康体检者作为对照组,均进行血脂水平和红细胞沉降率(ESR)、C反应蛋白(CRP)、类风湿因子(RF)检测。结果:活动期RA患者高密度脂蛋白胆固醇(HDL-C)水平均较非活动期组和对照组显著降低(P < 0.01),非活动期RA患者与对照组HDL-C水平差异无统计学意义(P > 0.05);活动期和非活动期RA患者的甘油三酯、总胆固醇、低密度脂蛋白胆固醇水平与对照组差异均无统计学意义(P > 0.05)。RA患者ESR与HDL-C呈负相关关系(P < 0.01),而CRP、RF和HDL-C均无相关关系。结论:RA患者体内血脂水平发生异常,炎症反应对脂代谢具有调节作用。
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| 关 键 词： | 关节炎 类风湿 血脂 炎症因子 高密度脂蛋白胆固醇 |
| 收稿时间： | 2010-04-19 |
The change of blood lipids in rheumatoid arthritis and its clinical significance |
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| ZHANG Song,LIU Gui-ling,ZHENG Lan. The change of blood lipids in rheumatoid arthritis and its clinical significance[J]. Journal of Bengbu Medical College, 2011, 36(2): 156-157,160 |
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| Authors: | ZHANG Song LIU Gui-ling ZHENG Lan |
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| Affiliation: | 1. Department of Blood Rheumatism, Bengbu Third People's Hospital, Bengbu Auhui 233000, China;2. Department of Clinical Laboratory, Bengbu Third People's Hospital, Bengbu Auhui 233000, China |
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| Abstract: | Objective:To observe the changes and the clinical significances of blood lipids in patients with rheumatoid arthritis(RA) in active phase.Methods:Fifty-six patients with RA(30 cases of active type,26 non-active) and 30 healthy controls were randomly chosen.Plasma lipids,erythrocyte sedimentation rate(ESR),C reactive protein(CRP) and rheumatoid factor(RF) were studied.All data were subjected to statistical analysis.Results:The high-density lipoprotein cholesterol(HDL-C) level in active RA group was significa... |
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| Keywords: | arthritis rheumatoid blood lipid inflammation factor high-density lipoprotein cholestrol |
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