| ELSD检测法测定银杏酮酯注射液中银杏内酯A，B的含量 |
| |
| 引用本文： | 吕伏生,陈伟,冯芳,张正行. ELSD检测法测定银杏酮酯注射液中银杏内酯A，B的含量[J]. 中国药科大学学报, 2001, 32(1): 36-38 |
| |
| 作者姓名： | 吕伏生 陈伟 冯芳 张正行 |
| |
| 作者单位： | 中国药科大学药物分析教研室， 南京 210009 |
| |
| 摘 要： | 目的测定银杏酮酯注射液中银杏内酯A、B的含量。方法采用高效液相色谱蒸发光散射检测器（ELSD）检测法测定银杏酮酯注射液中银杏内酯A，B的含量。色谱条件为大连依利特公司HypersilC18柱，5μm，250×4.6mm；水-甲醇-四氢呋喃（70∶25∶12）为流动相；蒸发光散射检测器检测参数漂移管温度105℃；载气（N
|
| 关 键 词： | 银杏酮酯注射液 银杏内酯 蒸发光散射检测器 高效液相色谱 |
| 文章编号： | 1000-5048(2001)01-0034-03 |
| 修稿时间： | 2000-05-19 |
The Contents ofTerpenelactones in the Ginkgo Injection |
| |
| Abstract: | AIM: To determin the content of ginkgolide A、B in the Ginkgoinjection. METHODS: The HPLC method with Evaporative Light Scattering Detector （ELSD）was established to determine the content of ginkgolide A,B in the Ginkgo injection. The analysis was carried out on C18 Column.The mobil phase is H2O-MeOH-THF(70∶25∶12) The operating conditions of the ELSD were obtained with a nebulizer nitrogen flow-rate of 2.95L/min and an evaporator tube temperature of 105℃. RESULTS: No interference was found in the ginklides peak situation.The method was simple，had good linear relationship. The relative standard deviation of the reproducibility were 1.88% and 1.64% respective and the average recovery were 98.5% and 97.7%, respectively. CONCLUSION: The method can be used for quality control. |
| |
| Keywords: | Ginkgolides High performance liquid chromatography Evaporative light scattering detecter |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《中国药科大学学报》浏览原始摘要信息 |
|
点击此处可从《中国药科大学学报》下载全文 |
