| 呋喃甲酰壳聚糖的制备、表征及其抗氧化活性 |
| |
| 引用本文： | 赵迪,王江涛.呋喃甲酰壳聚糖的制备、表征及其抗氧化活性[J].医学教育探索,2012,25(3). |
| |
| 作者姓名： | 赵迪 王江涛 |
| |
| 作者单位： | 中国海洋大学海洋化学理论和工程技术教育部重点实验室， 山东 青岛 266100;中国海洋大学海洋化学理论和工程技术教育部重点实验室， 山东 青岛 266100 |
| |
| 基金项目： | 国家自然科学基金项目（41076065）资助 |
| |
| 摘 要： | 以壳聚糖与呋喃甲酰氯反应得到呋喃甲酰壳聚糖。通过FT-IR、1H-NMR、X射线衍射、热重分析、溶解度实验、元素分析、抗氧化活性测试等手段对产物进行了结构和性能表征。结果表明：产物为目标产物且热稳定性好于壳聚糖；在水中的溶解性能良好，溶解度为0.04 g/mL；取代度为0.69；当对羟基自由基的清除率达到50%时，呋喃甲酰壳聚糖的质量浓度为 1.1 mg/mL，其还原能力随质量浓度增加而增强，抗氧化活性优于壳聚糖。
|
| 关 键 词： | 壳聚糖 呋喃甲酰壳聚糖 抗氧化活性 |
| 收稿时间： | 2012/6/25 0:00:00 |
Synthsis, Characterization and Antioxidant Activity of N-Furoyl Chitosan |
| |
| ZHAO Di and WANG Jiang-tao.Synthsis, Characterization and Antioxidant Activity of N-Furoyl Chitosan[J].Researches in Medical Education,2012,25(3). |
| |
| Authors: | ZHAO Di and WANG Jiang-tao |
| |
| Institution: | Key Laboratory of Marine Chemistry Theory and Technology of Ministry of Education, Ocean University of China, Qingdao 266100, Shandong, China;Key Laboratory of Marine Chemistry Theory and Technology of Ministry of Education, Ocean University of China, Qingdao 266100, Shandong, China |
| |
| Abstract: | N-furoyl chitosan was synthesized by the reaction of chitosan with the furoyl chloride. The structure and performance of the product was characterized by FT-IR, 1H-NMR, XRD, thermogravimetric analysis (TGA), solubility analysis, elemental analysis, antioxidant activity analysis. Results showed that the product was N-furoyl chitosan and the thermal stability of product was superior to chitosan and the solubility was 0.04 g/mL in water. The degree of substitution was 0.69. When hydroxyl radicals clearance rate reached 50%, the mass concentration of furoyloxy chitosan was 1.1 mg/mL. The reducing power of chitosan and product increased with their mass concentration increasing. The antioxidant activity of N-furoyl chitosan was stronger than that of chitosan. |
| |
| Keywords: | chitosan furoyl chitosan antioxidant activity |
|
| 点击此处可从《医学教育探索》浏览原始摘要信息 |
| 点击此处可从《医学教育探索》下载免费的PDF全文 |
|
