老年抑郁症治疗方案分析

目的:分析老年抑郁症治疗方案的特点和疗效,促进合理治疗。方法:采用自编表格收集51例住院病人的治疗情况并进行分析。结果:老年抑郁症病人首选SSRIs等新型抗抑郁药治疗,67%的病人采用改良电休克治疗(MECT),MECT合并药物治疗起效快、MECT组(n=34)比对照组(n=17)病人临床痊愈率高,分别为47%和12%(P<0.05);92%的病人合并使用苯二氮艹卓类药物。结论:住院老年抑郁症病人适用MECT合并新型抗抑郁药治疗,疗效明显优于单用药物治疗,心理治疗有待加强。

Analysis of treatment for depression in elderly

AIM: To analyze the characteristics and efficacy of treatment for the senile depression for promoting the proper management. METHODS: Fifty-one elder inpatients with depression were recruited. A special designed schedule was adopted to analyse the data of the result. RESULTS: SSRIs are recommended as the first choice antidepressants for the elder depressions. Modify electroconvulsive therapy (MECT) was applied to 67 % of the inpatients, and MECT combined pharmacotherapy showed higher efficacy including 34 (47 %) vs 17(12 %), respectively (P<0.05); and combined benzodiazepines were applied to 92 % patients. CONCLUSION: The treatment of elder depression of inpatients with MECT combined with SSRIS are more effective than single drug therapy, and furthermore psychotherapy is still being improved.