Anti-inflammatory effect of Solanum lycocarpum fruits |
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| Authors: | Vieira G Ferreira P M Matos L G Ferreira E C Rodovalho W Ferri P H Ferreira H D Costa E A |
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| Institution: | Instituto de Ciências Biológicas, Departamento de Ciências Fisiológicas, Universidade Federal de Goiás, Goiania, Brazil. |
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| Abstract: | The croton oil-induced mouse ear oedema test, acetic acid-induced abdominal writhing, and carrageenan-induced peritonitis were used to study the anti-inflammatory effects of the crude ethanol extract and its alkaloid fraction from Solanum lycocarpum fruits. The alkaloid fraction induced a dose-dependent reduction in ear oedema formation and leukocyte migration, suggesting that S. lycocarpum fruits may contain steroidal alkaloids accounting for the anti-inflammatory effect of the crude ethanol extract. |
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| Keywords: | Solanum lycocarpum anti‐in?ammatory effect ear oedema abdominal writhing peritonitis |
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