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Follow-up of Renin in Essential Hypertension
Authors:W H Birkenhäger  T L Kho  M A Schalekamp  G A Zaal  A Wester  P W de  Leeuw  R Vandongen  T D Fawzi-Meininger
Institution:Department of Internal Medicine, Zuiderziekenhuis, Rotterdam, The Netherlands
Abstract:Summary: Follow-up of renin in essential hypertension.
In a prospective study of patients with essential hypertension, plasma renin levels showed a progressive increase with longer follow-up. This was associated with a parallel increase in renal vascular resistance. Arterial blood pressure and plasma volume did not change significantly during follow-up. In patients where the hypertension was complicated by myocardial infarction there was a comparatively greater increase in renin levels and renal vascular resistance which may be attributable to chronic reduction of cardiac output.
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