砖茶型氟中毒成人的氟骨症

为了解砖茶型氟中毒在成人中的危害程度 ,运用总摄氟量调查 ,环境氟水平及尿氟含量测定 ,氟骨症临床体征检查及X线检查等 ,对西藏那曲县 111名 3 0～ 78岁成人进行了饮茶习惯 ,氟骨症患病情况调查。结果表明 ,那曲县水源氟浓度仅 (0 10± 0 0 3 )mg L ,但砖茶食物 -糌粑 ,酥油茶氟含量分别达到 (4 5 2± 0 74)mg kg和 (3 2 1± 0 65 )mg kg,他们每日每人总摄氟量达到 11 99mg ,其中 99%来自含砖茶的食物。氟骨症阳性体征检出率为 89% ,X线片确诊氟骨症患病率为 83 %。砖茶型氟骨症的阳性体征与X线片检查均表明 ,骨关节退行性变和骨间膜骨化 ,肌腱钙化是其主要特征 ,硬化型 (骨质增多 )氟骨症患病率占 74%。与我国饮水型、燃煤型氟中毒比较 ,砖茶型氟中毒对人体的危害更大

Brick-tea type adult bone fluorosis

To investigate health impact of brick-tea type fluorosis in adults, the total daily fluorine intake, environment fluorine level were determined, the average urinary fluorine content assay and bone X-ray examination were conducted, the clinical manifestations were observed in the brick-tea type bone fluorosis epidemiological study conducted in Naqu County, Tibet at September, 2001. One hundred and eleven adults aged at 30-78 year-old were enrolled. It was found that the fluorine level of drinking water in Naqu County was 0.10 +/- 0.03 mg/L, but the brick-tea water processed foods-zamba and buttered tea had fluorine content of 4.52 +/- 0.74 mg/kg and 3.21 +/- 0.65 mg/kg respectively. The adult daily fluorine intake reached 11.99 mg, among which 99% is originated from the brick-tea containing foods. Positive detection rate of fluorosis osteopathy was 89% and the X-ray film confirmed that the diagnosis rate was 83%. Degenerative arthropathy and ossification of the interosteal membrane, calcification of the tendon were the characteristics that indicated by both the positive signs and reogenological examination. The prevalence of osteosclerosis type (bone matrix increased) was 74%. It is suggested that there were even more severe health impact compared with those in the water type and coal combustion type fluorosis.