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90例儿童中成药不良反应报告分析
引用本文:王彬,赵汝霞.90例儿童中成药不良反应报告分析[J].儿科药学杂志,2022,28(10):20-22.
作者姓名:王彬  赵汝霞
作者单位:海口市妇幼保健院,海南海口 570203
摘    要:摘要]目的:探讨儿童应用中成药所致不良反应(ADR)发生特点及规律,为促进临床合理用药提供参考。方法:采用回顾性分析方法,选取海口市妇幼保健院2012-2019年上报至国家药品不良反应监测中心的90例中成药所致ADR报告进行统计分析。结果:90例ADR中,1~6岁儿童ADR发生率最高(72.22%);静脉滴注是引发ADR最主要的给药途径(82.80%);清热解毒类中药注射剂导致的ADR最多,与呼吸系统疾病发生率较高有关;ADR以皮肤及其附件损害为主(82.76%)。结论:临床应重视儿童中成药的应用,加强ADR监测,以降低ADR发生率,促进临床合理用药。

关 键 词:中药不良反应  监测  合理用药

Analysis of 90 Cases of Adverse Drug Reactions Induced by Chinese Patent Medicine in Children
Wang Bin,Zhao Ruxia.Analysis of 90 Cases of Adverse Drug Reactions Induced by Chinese Patent Medicine in Children[J].Journal of Pediatric Pharmacy,2022,28(10):20-22.
Authors:Wang Bin  Zhao Ruxia
Institution:Haikou Hospital of the Maternal and Child Health, Haikou 570203, China
Abstract:Abstract] Objective: To probe into the characteristics and rules of adverse drug reactions (ADR) induced by Chinese patent medicine in children, so as to provide reference for promoting clinical rational drug use. Methods: Retrospective analysis was adopted, 90 cases of ADR induced by Chinese patent medicine reported to the National Adverse Drug Reaction Monitoring Center in Haikou Hospital of the Maternal and Child Health from 2012 to 2019 were selected for statistical analysis. Results: Of the 90 cases of ADR, the incidence of ADR in children aged from 1 to 6 years was the highest (72.22%). The most of ADR cases were induced by intravenous injection (82.80%). The antipyretic and detoxifying Chinese patent medicine injection were the major cause of ADR in respect of the drug types, which was related to the high incidence of respiratory diseases. The skin and its appendages were mainly damaged in ADR (82.76%). Conclusion: Clinical attention should be paid to the application of Chinese patent medicine in children, and ADR monitoring should be strengthened to reduce the incidence of ADR and promote clinical rational drug use.
Keywords:adverse drug reactions induced by Chinese patent medicine  monitoring  rational drug use
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