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Avelumab plus standard-of-care chemoradiotherapy versus chemoradiotherapy alone in patients with locally advanced squamous cell carcinoma of the head and neck: a randomised,double-blind,placebo-controlled,multicentre, phase 3 trial
Authors:Nancy Y Lee  Robert L Ferris  Amanda Psyrri  Robert I Haddad  Makoto Tahara  Jean Bourhis  Kevin Harrington  Peter Mu-Hsin Chang  Jin-Ching Lin  Mohammad Abdul Razaq  Maria Margarida Teixeira  József Lövey  Jerome Chamois  Antonio Rueda  Chaosu Hu  Lara A Dunn  Mikhail Vladimirovich Dvorkin  Steven De Beukelaer  Ezra Cohen
Affiliation:1. Memorial Sloan Kettering Cancer Center, New York, NY, USA;2. UPMC Hillman Cancer Center, Pittsburgh, PA, USA;3. Attikon University Hospital, National Kapodistrian University of Athens, Athens, Greece;4. Dana-Farber Cancer Institute, Boston, MA, USA;5. National Cancer Center Hospital East, Kashiwa, Japan;6. Centre Hospitalier Universitaire Vaudois, Lausanne, Vaud, Switzerland;7. The Royal Marsden Hospital–The Institute of Cancer Research National Institute for Health Research Biomedical Research Centre, London, UK;8. Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan;9. Department of Radiation Oncology, Changhua Christian Hospital, Changhua, Taiwan;10. Stephenson Cancer Center, University of Oklahoma, Oklahoma, OK, USA;11. Instituto Português de Oncologia de Coimbra Francisco Gentil, EPE, Coimbra, Portugal;12. Országos Onkológiai Intézet, Sugárterápiás Osztály Semmelweis Egyetem, Onkológiai Tanszék, Budapest, Hungary;13. Centre Hospitalier Prive Saint Gregoire, Saint Gregoire, France;14. Medical Oncology, Costa del Sol Sanitary Agency and Regional University Hospital, IBIMA, Málaga, Spain;15. Fudan University Cancer Hospital, Xuhui, Shanghai, China;p. Memorial Sloan Kettering Cancer Center, New York, NY, USA;q. Budgetary Institution of Healthcare of the Omsk Region, Clinical Oncology Dispensary, Omsk, Russia;r. Pfizer, Zürich, Switzerland;s. Pfizer, La Jolla, CA, USA;t. Moores Cancer Center, UC San Diego Health, La Jolla, CA, USA
Abstract:
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