117例血液病患儿医院内感染分析与对策

目的：预防血液病患儿医院内感染的发生。方法：用回顾性调查方法。结果：医院内感染发生率为62.39%。感染部位以上呼吸道为主，占46.57%。住院时间越长，感染发生率越高，其中致病菌以革兰阴性菌为主，占19.26%。革兰阳性致病菌占15.59%，真菌占7.33%。药敏实验对第二代头孢菌素耐药性增加，肠球菌对青霉素类，部分头孢第二代产生耐药。结论：医院内感染与住院时间患儿免疫力低下与抗生素应用密切相关。病原菌的耐药率呈增加趋势，故保护性隔离，抗生素合理应用尤为重要。

Analysis and treatment measure of nosocomial infection of 117 cases of blood disease in chldren.

Object:To prevent the occurrence of nosocomial infection of blood disease in chldren Methods:The method of retrospective investigation was used.Results:The incidence of nosocomial infection was 62.39%.The main region of infection was superior respiratory tract,which was 46.57%.The longer the patients were hospitalization,the higher the incidence of nosocomial infection.Occurred:In all these pathogenic germs,the main germ was Gram-negative germ,which was 19.26%,Gram-positive germ was 15.59%,fungus was about 7.33%.The drug resistance of germs on second generation Cephalosporin was increasing in the drug sensitive test.The intestine cocci also produced the drug resistance on Penicillins and part second generation Cephalosporins.Conclusion:The nosocomial infection is closely related with morbid children hypoimmunity in hospitalization.The drug resistance of germs is tending to increase.So the protective isolation and rational selection antibiotic are even more important.