全间歇短程化疗方案治疗新发涂阳肺结核的远期疗效分析

目的 世界银行贷款中国结核病控制项目首次将全间歇短程化疗（短化）方案［２Ｈ３Ｒ３Ｚ３Ｓ３（Ｅ３）／４Ｈ３Ｒ３］应用于国家结核病控制规划，取得了满意的近期疗效。为评价方案的有效性，将进行远期效果观察。方法 对１２个项目省、自治区５６个示范县１９９２年全年登记的新发涂阳患者，在治愈后２年进行了结核分支杆菌涂片检查，以了解细菌学复发情况。结果 ４４００例治愈患者经痰涂片检查，发现１３５例痰菌复阳，复发率

Long-term efficacy of full course intermittent short-course chemotherapy on new smear positive tuberculosis patients

Objective TO evaluate the long term efficacy of full course intermittent short course chemotherapy[2H 3R 3Z 3S 3(E 3)/4H 3R 3],which has first been used in the National Tuberculosis Control Programme with the loan from the World Bank and its satisfactory short term efficacy has been achived,on new smear positive tuberculosis patients.Method All new smear positive tuberculosis patients,registered by 56 counties of 12 project provinces and autonomous regions in 1992,were investigated to find out the bacteriological relapse rate 2 years after treatment.Result One hundred thirty five out of 4400 patients followed up were found smear positive,with arelapse rate of 3.1%.Conclusion The result suggests that the chemotherapy should be given a priority in the National Tuberculosis Control Programme because of its high cure rate.