| 参芎嗪注射液对大鼠脑缺血损伤血液流变学、脑含水量的影响 |
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| 引用本文： | 韩辉,吴丽敏,杨文明,汪美霞,董婷,汪瀚,韩明向.参芎嗪注射液对大鼠脑缺血损伤血液流变学、脑含水量的影响[J].中西医结合心脑血管病杂志,2010,8(1):71-73. |
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| 作者姓名： | 韩辉 吴丽敏 杨文明 汪美霞 董婷 汪瀚 韩明向 |
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| 作者单位： | 1. 安徽中医学院第一附属医院,230031
2. 安徽省立医院 |
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| 摘 要： | 目的复制脑缺血大鼠模型,研究参芎嗪注射液对实验性脑缺血大鼠的干预作用。方法通过线栓法复制大鼠脑缺血模型,设立假手术组、模型组、川芎嗪注射液组、参芎嗪注射液组,观察各组治疗前后血液流变学、脑含水量、脑指数的影响。结果参芎嗪注射液可改善血液流变学,降低脑含水量及脑指数,与模型组比较差异有统计学意义(P0.05或P0.01)。结论参芎嗪注射液可改善微循环、减轻脑水肿,对脑缺血损伤起到较好的保护作用。
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| 关 键 词： | 参芎嗪注射液 川芎嗪注射液 脑缺血 血液流变学 脑水肿 |
Effect of Shenxiongqin Injection on Hemorheology and Cerebral Water Content in Rats with Focal Cerebral Ischemia |
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| Han Hui,Wu Limin,Yang Wenmin,et al Beijing University of Traditional Chinese Medicines.Effect of Shenxiongqin Injection on Hemorheology and Cerebral Water Content in Rats with Focal Cerebral Ischemia[J].Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease,2010,8(1):71-73. |
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| Authors: | Han Hui Wu Limin Yang Wenmin Beijing University of Traditional Chinese Medicines |
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| Institution: | Han Hui,Wu Limin,Yang Wenmin,et al Beijing University of Traditional Chinese Medicines(Beijing 100029) |
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| Abstract: | Objective To observe the effects of Shenxiongqin injection on hemorheology,cerebral water content in rats with focal cerebral ischemia. Methods Model rats with focal cerebral ischemia were established with the suture-occluded method and randomly divided into four groups:Sham group,model group,Chuanxiongqin injection group and Shenxiongqin injection group.The cerebral constitution parameters,including hemorheology,cerebral index and cerebral water content in rats with focal cerebral ischemia were observed. R... |
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| Keywords: | Shenxiongqin injection Chuanxiongqin focal cerebral ischemia hemorheology cerebral edema |
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