| 钩藤中吲哚类生物碱化学成分及药理活性研究进展 |
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| 引用本文： | 宋欣濛,薛睿,季宇彬.钩藤中吲哚类生物碱化学成分及药理活性研究进展[J].亚太传统医药,2014(5):64-68. |
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| 作者姓名： | 宋欣濛 薛睿 季宇彬 |
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| 作者单位： | [1]哈尔滨商业大学生命科学与环境科学研究中心,黑龙江哈尔滨150076 [2] 中国科学院上海药物研究所,上海,201203 |
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| 基金项目： | 国家科技重大专项《重大新药创制》课题资助（2012zx0930looi） |
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| 摘 要： | 钩藤,原名钓藤,入药历史悠久,主要用来治疗风热头痛、头晕目眩、小儿惊厥、高血压等症状.近年来,大量药理实验证明,钩藤中的主要活性成分是吲哚类生物碱.就钩藤中的吲哚类生物碱的化学成分及其药理活性进行系统性综述,为进一步开发利用中药钩藤提供理论依据.
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| 关 键 词： | 钩藤 吲哚生物碱 化学成分 药理活性 综述 |
A Review about the Chemical Constituents and Pharmacological Activities of Indole Alkaloids from Uncaria Rhynchophylla |
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| Song Xinmeng,Xue Rui,Huang Chenggang,Ji Yubin.A Review about the Chemical Constituents and Pharmacological Activities of Indole Alkaloids from Uncaria Rhynchophylla[J].Asia-Pacific Traditional Medicine,2014(5):64-68. |
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| Authors: | Song Xinmeng Xue Rui Huang Chenggang Ji Yubin |
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| Institution: | 1. Center of Research and Development on Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbin 150076, China 2. Shanghai Institute of Materia Medica Chinese Academy of Sciences, Shanghai 201203 ,China) |
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| Abstract: | Uncaria rhynchophylla （Miq.） Jacks, formerly known as Diao-teng, has been widely used in clinic for a long time and mainly used for the treatment of fever and headache, faint and dizzy, infantile convulsion and hypertension. A large amount of phar- macological experiments indicate that the indole alkaloids are the main active ingredients of Uncaria rhynchophylla. Reviewed the constituents and pharmacological activities of the main indole alkaloids of Uncaria rhynchophylla, which could provide theoretical ba- sis to further develop and utilize the Uncaria rhynchophylla. |
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| Keywords: | Uncaria Rhynchophylla Indole Alkaloids Chemical Constituents Pharmacological Activities Review |
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