| 鱼腥草注射液的细菌内毒素检查 |
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| 引用本文： | 张建国. 鱼腥草注射液的细菌内毒素检查[J]. 药学实践杂志, 2006, 24(4): 216-218 |
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| 作者姓名： | 张建国 |
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| 作者单位： | 山东高密市人民医院,山东,高密,261500 |
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| 摘 要： | 目的：建立鱼腥草注射液细菌内毒素检查法。方法：按《中国药典》2000年版二部收载的细菌内毒素检查法要求，确定样品最大有效稀释倍数，进行鱼腥草注射液细菌内毒素干扰试验结果：鱼腥草注射液1：2倍稀释用入为0.5EU／mL鲎试剂捡查细菌内毒素存在抑制性干扰，1：4稀释用入为0．25EU/mL鲎试剂可消除干扰因素，可有效检测该药细菌内毒素结论：鲎试验法可用于鱼腥草注射液细菌内毒素检查，控制热原。
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| 关 键 词： | 鱼腥草注射液 细菌内毒素 干扰试验 鲎试剂 |
| 文章编号： | 1006-0111(2006)04-0216-03 |
| 收稿时间： | 2005-10-31 |
| 修稿时间： | 2005-10-31 |
Bacterial endotoxin test of Houttuynia injection |
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| ZHANG Jian-guo. Bacterial endotoxin test of Houttuynia injection[J]. The Journal of Pharmaceutical Practice, 2006, 24(4): 216-218 |
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| Authors: | ZHANG Jian-guo |
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| Affiliation: | Gaomi People's Hospital of Shandong,Gaomi 261500,China |
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| Abstract: | Objective:To explore a bacterial endotoxin test for Houttuynia cordata injection. Methods:The bacterial endoloxin test was experimented according to the requirement of the second volum of China Pharmacopoeia,2000 edition. Results:The interference factors could be excluded in the Houttuynia cordata diluted to 4 times, the bacterial endotoxin could be determined effectively by 0. 25 EU/mL of TAL.Conclusion:The pyrogen notoxin in Houttuynia cordata injection can be determined by LLA. |
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| Keywords: | Houttuynia cordata injection bacterial endotoxin interference experiment tachypleus amebocyte lysale(TAL) |
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