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Long-term follow-up and metal ion trend of patients with metal-on-metal total hip arthroplasty
Authors:Mitchell Bernstein  Nicholas M Desy  Alain Petit  David J Zukor  Olga L Huk  John Antoniou
Institution:Division of Orthopaedic Surgery, McGill University Health Centre, 1650 Cedar Avenue, Room B5.159.6, Montreal, Quebec, Canada, H3G 1A4.
Abstract:

Purpose

Long-term studies are required to support the use of metal-on-metal (MoM) bearings in total hip arthroplasty (THA) given the concern about systemic metal ion release and reports of adverse local soft tissue reactions. The purpose of this study was to report the seven to 13-year clinical, radiographic, and metal ion results in patients following MoM THA.

Methods

We studied 163 prostheses after second-generation MoM THA between July 1997 and November 2003. Cobalt and chromium metal ions were collected using whole and analysed by inductively-coupled plasma-mass spectrometry.

Results

The mean follow-up was 8.87 years (range, 7–13 years). Four hips (2.5 %) were revised. The Kaplan-Meier survivorship was 91.3 % for revision for all causes, and 97.5 % when excluding the hips revised for a manufacturer’s defect. Median whole blood cobalt levels peaked at a value of 2.87 μg/L at four years (p?p?=?0.002 vs. four years). Median chromium levels maximally increased up to 0.75 μg/L after five years (p?ConclusionsThis seven to 13-year follow-up study indicates that the clinical and radiological results following MoM THA are satisfactory with low revision rates. Cobalt and chromium ion levels peaked at four and five years, respectively, and gradually decreased thereafter.
Keywords:
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