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Quantification of total and unbound cefuroxime in plasma by ultra-performance liquid chromatography tandem mass spectrometry in a cohort of critically ill patients with hypoalbuminemia and renal failure |
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| Authors: | Joost J van Raaij Noortje J D Mabelis Kimberly N Shudofsky Sjoerd D Meenks Jos L M L le Noble Paddy K C Janssen |
| Institution: | 1. Department of Hospital Pharmacy, VieCuri Medical Centre, Venlo, The Netherlands;2. Department of Intensive Care, VieCuri Medical Centre, Venlo, The Netherlands
Department of Pharmacology and Toxicology, Maastricht University, The Netherlands |
| Abstract: | |
| Keywords: | cefuroxime hypoalbuminemia intensive care unit therapeutic drug monitoring unbound concentration |