Highlights of aliphatic C(sp3)-H hydrogen isotope exchange reactions |
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| Authors: | Mégane Valero Volker Derdau |
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| Affiliation: | R&D, Integrated Drug Discovery, Isotope Chemistry, Sanofi Germany, Frankfurt, Germany |
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| Abstract: | This review summarizes the highlights of aliphatic C (sp3)-H carbon hydrogen isotope exchange (HIE) methods developed in the last 10 years. In particular, new highly selective and reactive protocols in the areas of nanoparticle and metal-catalyzed homogeneous catalysis are reported. |
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| Keywords: | catalysis deuterium hydrogen isotope exchange tritium |
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