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The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells,reduces their proliferation,and attenuates neuropathic pain |
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| Authors: | Christophe Gattlen Alexandru-Florian Deftu Raquel Tonello Yuejuan Ling Temugin Berta Violeta Ristoiu Marc René Suter |
| Affiliation: | 1. Pain Center, Department of Anesthesiology, Lausanne University Hospital and University of Lausanne (CHUV), Lausanne, Switzerland Faculty of Biology and Medicine (FBM), University of Lausanne (UNIL), Lausanne, Switzerland;2. Pain Center, Department of Anesthesiology, Lausanne University Hospital and University of Lausanne (CHUV), Lausanne, Switzerland Faculty of Biology and Medicine (FBM), University of Lausanne (UNIL), Lausanne, Switzerland Department of Anatomy, Animal Physiology and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania;3. Pain Research Center, Department of Anesthesiology, University of Cincinnati Medical Center, Cincinnati, Ohio, USA;4. Pain Research Center, Department of Anesthesiology, University of Cincinnati Medical Center, Cincinnati, Ohio, USA Pain Research Laboratory, Institute of Nautical Medicine, Jiangsu Key Laboratory of Neurodegeneration, University of Nantong, Nantong, Jiangsu, China;5. Department of Anatomy, Animal Physiology and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania;6. Pain Center, Department of Anesthesiology, Lausanne University Hospital and University of Lausanne (CHUV), Lausanne, Switzerland |
| Abstract: | |
| Keywords: | Kir2.1 membrane potential microglia neuropathic pain proliferation |