阻塞性睡眠呼吸暂停低通气综合征与心脑血管疾病关系的研究进展

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是一种发病率较高而诊断率低,并具有一定潜在危险的疾患。近年来研究证实,OSAHS与高血压、冠心病、心力衰竭、心律失常、肺源性心脏病、脑卒中等心脑血管疾病的发生有着密切的关系。正确认识OSAHS与心脑血管疾病的关系有助于疾病的早期诊治,提高患者的生活质量。现对OSAHS与心脑血管疾病相关的流行病学及病理生理机制进行综述。

Research Progress of the Relationship between Obstructive Sleep Apnea Hypopnea Syndrome and Cardiovascular-Cerebrovascular Diseases

Sleep apnea hypopnea syndrome(OSAHS)is a potentially life-threatening disease,with a high incidence but a low diagnosis rate.In recent years,extensive studies have confirmed that OSAHS is closely associated with the occurrence of the cardiovascular and cerebrovascular diseases,such as hypertension,coronary heart disease,heart failure,arrhythmia,pulmonary heart disease,and stroke.Correct understanding of the association of OSAHS with cardiovascular and cerebrovascular diseases can contribute to the early diagnosis and treatment of such diseases and to improve the quality of life of patients.In this article,the relevant epidemiology and pathophysiological mechanisms between OSAHS and cardiovascular and cerebrovascular diseases were reviewed.