HIV-associated endometritis |
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Authors: | M Peuchmaur D Emilie R Vazeux J C Pons J F Delfraissy G Lemaigre P Galanaud |
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Affiliation: | Service de Pathologie, H?pital A. Béclère, Paris, France. |
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Abstract: | Using immunohistochemical staining, in situ hybridization and a combination of both, we demonstrate here the replication of HIV in the endometrial stroma. Infected cells do not belong to the T-lymphocyte lineage but rather to a monocyte-macrophage cell type. This report suggests a possible relationship between HIV infection and endometritis. Moreover, HIV replication in endometrial tissues could play a role in heterosexual and materno-fetal transmission. |
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