| 儿童病毒性肝炎PHSA受体、DNA聚合酶、抗HBc-IgM和抗HAV-IgM的临床研究 |
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| 引用本文： | 王慕琪,仇红霞,吴芸,童荪,吴建宏,孙增璞. 儿童病毒性肝炎PHSA受体、DNA聚合酶、抗HBc-IgM和抗HAV-IgM的临床研究[J]. 苏州大学学报(自然科学版), 1988, 0(3) |
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| 作者姓名： | 王慕琪 仇红霞 吴芸 童荪 吴建宏 孙增璞 |
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| 作者单位： | 苏州市第五人民医院传染科，苏州市第五人民医院传染科，苏州市第五人民医院传染科，苏州市第五人民医院免疫室，苏州市第五人民医院免疫室，苏州市第五人民医院免疫室 校友 |
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| 摘 要： | 本文应用ELISA法测定了41例儿童病毒性肝炎患儿血清的PHSA受体、抗HBc-IgM和抗HBV-IgM,并用RIA法测其DNA聚合酶(DNA-P)的活性。按病原分型在32例急性黄疸肝炎中有6例为甲肝(18.7%),10例为乙肝(31.3%),10例为甲乙型肝炎混合感染(31.3%),6例为非甲非乙型肝炎(18.7%);5例急性无黄疸型肝炎中判为乙肝3例,非甲非乙型肝炎2例;4例慢性迁延型肝炎全系乙型肝炎。发现PHSA受体,DNA-P和抗HBc-IgM的检测对乙型病毒性肝炎近期感染的诊断,具有特异性和敏感性。
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| 关 键 词： | 多聚人血清白蛋白受体(PHSA-R) DNA-P 抗HBc-IgM 抗HAV-IgM |
A Serological Study of PHSA-R, DNA-P, Anti-HBC/IgM and Anti-HAV/IgM in Childhood Viral Hepatitis |
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| Wang Muqi et al. A Serological Study of PHSA-R, DNA-P, Anti-HBC/IgM and Anti-HAV/IgM in Childhood Viral Hepatitis[J]. Suzhou University Journal of Medical Science, 1988, 0(3) |
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| Authors: | Wang Muqi et al |
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| Affiliation: | Wang Muqi et al |
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| Abstract: | This study have detected the PHSA-R, anti-HBC/IgM and antiHAV/IgM by ELISA method and DNA-P by RIA method in 41 pediatric patients with viral hepatitis. During the acute hepatitis with jaundice in 32 instances, we classified 10(31.3%) of hepatitis-B, 10(31.3%) of hepatitis-A and-B, 6(18.7%) hepatitis-A and 6(18.7%)of NANB. While in 9 instances of acute hepatitis without jaundice, we found 4 of chronic persistent hepatitis of HVB-type, 3 of hepatitis-B and 2 of NANB. It is suggested that PHSAR, DNA-P and anti-HBC/IgM may be employed as sensitive method in the detection of recent infections stage of HBV. |
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| Keywords: | polymerized human serum albumin receptor(PHSA-R) DNA polymerase(DNA-P) anti-HBC/IgM anti-HAV/IgM |
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