| 肝脏缺血再灌注损伤保护机制的研究进展 |
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| 引用本文： | 李斌,钱海鑫.肝脏缺血再灌注损伤保护机制的研究进展[J].中国现代医生,2011,49(25):28-30. |
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| 作者姓名： | 李斌 钱海鑫 |
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| 作者单位： | 1. 嘉兴市第二医院普外科,浙江嘉兴,314000
2. 苏州大学附属第一医院普外科,江苏苏州,215006 |
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| 摘 要： | 肝脏缺血再灌注损伤是肝脏外科中常见的病理生理现象，微循环障碍、氧自由基过多及细胞凋亡等是引起损伤的重要机制，而研究发现热休克蛋白、一氧化氮、内皮素、血红素氧化酶、某些细胞因子及基因有保护肝脏、降低肝脏缺血再灌注损伤的作用，进一步研究其保护机制，对研究肝脏疾病有重要的临床意义。
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| 关 键 词： | 肝脏 缺血再灌注损伤 保护机制 |
Advances in Defense Mechanism of Hepatic Ischemia-reperfusion Injury |
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| Authors: | LI Bin QIAN Haixin |
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| Institution: | LI Bin1 QIAN Haixin2 1.The Second Hospital of Jiaxing City,Jiaxing 314000,China,2.The Affilied First Hospital of Suzhou University,Suzhou 215006 |
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| Abstract: | Hepatic ischemia-reperfusion injury is a common pathophysiological phenomenon in liver surgery,that caused by microcirculatorydisturbance,oxygen free radicals,apoptosis,and so on.Study found that heat shock protein,nitric oxide,endothelins,heme oxygenase,some cytokines and genes can protect the liver and reduce hepatic ischemia-reperfusion injury.It has important clinical significance in hepatic disease,so to further study the defense mechanism of hepatic ischemia-reperfusion injury. |
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| Keywords: | Hepar Ischemia-reperfusion injury Defense mechanism |
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