组织因子、组织因子途径抑制物与妇科肿瘤术后深静脉血栓形成的关系

目的检测妇科肿瘤术后下肢深静脉血栓形成的患者血浆中组织因子（TF）、组织因子途径抑制物（TFPI一1）水平的变化，探讨其与妇科肿瘤术后深静脉血栓形成的相关性。方法用ELISA法分别检测妇科良恶性肿瘤术后患者血浆TF、TFPI一1水平的变化。结果无深静脉血栓形成的妇科恶性肿瘤组TF水平显著高于子宫肌瘤及健康对照组（P〈0．01），妇科恶性肿瘤组TFPI一1水平高于子宫肌瘤及健康对照组（P〈0．05），子宫肌瘤与健康对照组比较差异无统计学意义（P〉0．05）。深静脉血栓形成妇科恶性肿瘤组TF水平显著高于子宫肌瘤及健康对照组（P〈0．01），有深静脉血栓形成妇科恶性肿瘤组TFPI一1水平与无深静脉血栓形成妇科恶性肿瘤组相比之间无统计学差异（P〉0．05），子宫肌瘤与健康对照组比较差异无统计学意义（P〉0．05）。结论妇科肿瘤术后深静脉血栓形成患者组织因子明显增高，TF、TFPI一1可作为榆涮电｜科肿瘤尤苴县妇科恶忡肿瘤术后深静H永向柃形成的雷兽指标．

Relationship between Plasma Tissue Factor and Tissue Factor Pathway Inhibitor and Gynecologic Tumors Patients with Postoperative Deep Venous Thrombosis

Objective To investigate the relationship between tissue factor(TF),tissue factor pathway inhibitor(TFPI-1)and postoperative deep venous thrombosis in patients with gynecological tumors by measuring the plasma levels of TF and TFPI-1.Methods Seventy two patients with gynecological tumors were enrolled and the plasma levels of TF and TFPI-1 antigen were measured by ELISA method.Results Of no deep vein thrombosis groups,the plasma levels of TF in gynecological tumors group were significantly higher than that ...