组织因子、组织因子途径抑制物与妇科肿瘤术后深静脉血栓形成的关系 |
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引用本文: | 杨黎,王若琳,刘伟靓.组织因子、组织因子途径抑制物与妇科肿瘤术后深静脉血栓形成的关系[J].中国现代医生,2011,49(25):61-62. |
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作者姓名: | 杨黎 王若琳 刘伟靓 |
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作者单位: | 1. 郑州大学第二附属医院妇产科,河南郑州,450014 2. 郑州人民医院妇产科,河南郑州,450003 |
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摘 要: | 目的检测妇科肿瘤术后下肢深静脉血栓形成的患者血浆中组织因子(TF)、组织因子途径抑制物(TFPI一1)水平的变化,探讨其与妇科肿瘤术后深静脉血栓形成的相关性。方法用ELISA法分别检测妇科良恶性肿瘤术后患者血浆TF、TFPI一1水平的变化。结果无深静脉血栓形成的妇科恶性肿瘤组TF水平显著高于子宫肌瘤及健康对照组(P〈0.01),妇科恶性肿瘤组TFPI一1水平高于子宫肌瘤及健康对照组(P〈0.05),子宫肌瘤与健康对照组比较差异无统计学意义(P〉0.05)。深静脉血栓形成妇科恶性肿瘤组TF水平显著高于子宫肌瘤及健康对照组(P〈0.01),有深静脉血栓形成妇科恶性肿瘤组TFPI一1水平与无深静脉血栓形成妇科恶性肿瘤组相比之间无统计学差异(P〉0.05),子宫肌瘤与健康对照组比较差异无统计学意义(P〉0.05)。结论妇科肿瘤术后深静脉血栓形成患者组织因子明显增高,TF、TFPI一1可作为榆涮电|科肿瘤尤苴县妇科恶忡肿瘤术后深静H永向柃形成的雷兽指标.
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关 键 词: | 组织因子 组织因子途径抑制物 妇科肿瘤 深静脉血栓形成 |
Relationship between Plasma Tissue Factor and Tissue Factor Pathway Inhibitor and Gynecologic Tumors Patients with Postoperative Deep Venous Thrombosis |
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Authors: | YANG Li WANG Ruolin LIU Weiliang |
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Institution: | YANG Li1 WANG Ruolin2 LIU Weiliang2 1.Department of Obstetrics and Gynecology,the Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450014,China,2.Department of Obstetrics and Gynecology,People's Hospital of Zhengzhou City,Zhengzhou 450003 |
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Abstract: | Objective To investigate the relationship between tissue factor(TF),tissue factor pathway inhibitor(TFPI-1)and postoperative deep venous thrombosis in patients with gynecological tumors by measuring the plasma levels of TF and TFPI-1.Methods Seventy two patients with gynecological tumors were enrolled and the plasma levels of TF and TFPI-1 antigen were measured by ELISA method.Results Of no deep vein thrombosis groups,the plasma levels of TF in gynecological tumors group were significantly higher than that ... |
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Keywords: | Tissue factor Tissue factor pathway inhibitor Gynecologic tumor Deep venous thrombosis |
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