Evaluation of anaerobic flora in lung neoplasms

Purpose of this study was to analyse the kind and frequency of anaerobic bacteria in the lower respiratory tract as well as susceptibility of the bacteria to antibiotics. Material from 35 patients with lung tumour derived from tumour and post-tumoural area sample. Collected sample was cultivated in anaerobic and aerobic conditions. Anaerobic bacteria were found in 23 (66%) samples. Totally there were 44 isolated of anaerobic bacteria strains. The most common G-negative strains belonged to genus of Bacteroides (11 strains); two types dominated: Bacteroides gracilis (4 strains) Bacteroides fragilis (4 strains). Among G-positive anaerobic bacteria most common were Peptostreptococcus (9 strains). G-positive rods were represented by Propionibacterium genus (8 strains). The susceptibility of anaerobic bacteria was estimated towards mostly used antibacterial drugs. Results suggest that most of bacteria were susceptible for imipenem, piperacillin/tazobactam, amoxicillin/clavulanate, ampicillin/sulbactam, metronidazole, piperacillin and clindamycin. Bacteria were less susceptible to roxitromycin and examined cephalosporins. Most of the strains were resistant for cefuroxime.