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| 支气管哮喘患儿血浆中IL-9的检测及临床意义 | |
| 引用本文： | 徐庆雷,周红,王洪建,胡礼仪,马斌,仝佳,陈建国,王胜军. 支气管哮喘患儿血浆中IL-9的检测及临床意义[J]. 检验医学与临床, 2010, 7(23): 2563-2564. DOI: 10.3969/j.issn.1672-9455.2010.23.002 |
| 作者姓名： | 徐庆雷 周红 王洪建 胡礼仪 马斌 仝佳 陈建国 王胜军 |
| 作者单位： | 1. 江苏省沭阳县人民医院检验科,223600 2. 江苏大学免疫学和免疫检验学系,212013 3. 江苏大学附属人民医院,212002 |
| 基金项目： | 江苏省教育厅自然科学基金 |
| 摘 要： | 目的检测支气管哮喘患儿血浆中白细胞介素-9(IL-9)的水平,探讨IL-9在支气管哮喘发生发展中的意义。方法收集支气管哮喘患儿和健康对照外周血标本。采用酶联免疫吸附试验(ELISA)检测血浆中IL-9和总IgE浓度。结果支气管哮喘急性发作期患儿血浆IL-9水平高于健康对照组(P0.05),而临床缓解组和健康对照组比较,差异无统计学意义(P0.05)。支气管哮喘急性发作期患儿血浆IL-9水平与总IgE浓度呈正相关。结论支气管哮喘患儿血浆中IL-9水平升高,与疾病的发生发展关系密切。 |
| 关 键 词： | 支气管哮喘 白细胞介素-9 酶联免疫吸附试验 |
Level of plasma IL-9 in children with bronchial asthma |
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| XU Qing-lei,ZHOU Hong,WANG Hong-jian,HU Li-yi,MA Bin,TONG Jia,CHEN Jian-guo,WANG Sheng-jun. Level of plasma IL-9 in children with bronchial asthma[J]. Laboratory Medicine and Clinic, 2010, 7(23): 2563-2564. DOI: 10.3969/j.issn.1672-9455.2010.23.002 | |
| Authors: | XU Qing-lei ZHOU Hong WANG Hong-jian HU Li-yi MA Bin TONG Jia CHEN Jian-guo WANG Sheng-jun |
| Affiliation: | 1.Department of Clinical Laboratory,Shuyang County People′s Hospital,Shuyang,Jiangsu 223600,China;2.Department of Immunology,Jiangsu University,Zhenjiang,Jiangsu212013,China;3.Affiliated People′s Hospital of Jiangsu University,Zhenjiang,Jiangsu 212002,China |
| Abstract: | Objective To investigate the level of the plasma IL-9 in children with bronchial asthma.Methods The concentrations of plasma IL-9 and total IgE were detected by enzyme linked immunosorbent assay（ELISA） in bronchial asthma and healthy control volunteers.Results The IL-9 concentrations in the group of children with bronchial asthma without treatment were markedly higher than that in the healthy controls（P0.05）,but there were no significant differences between the groups of bronchial asthma in clinical remission and healthy controls（P0.05）.Furthermore,the result showed the positively correlation between IL-9 and total IgE in untreated asthma bronchial patients.Conclusion IL-9 is higher in children with bronchial asthma without treatment,which suggesting that IL-9 might be involved in the pathological process of bronchial asthma. |
| Keywords: | asthma bronchial IL-9 enzyme linked immunosorbent assay |
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